Prevalence of Novel Risk Factors in Patients of Acute Coronary Syndrome in Eastern India: A Detailed Analysis

Sudeb Mukherjee, Kaushik Manna, Suhana Datta


Background: To  identify  prevalence  of   the  novel  risk  factors  among  young  patients   with  Acute  Coronary  Syndrome  (ACS)  and  having  no  or  minimal  conventional  risk factors.

Methods: Total  70  patients  ( male  48 ,  female 22 )   who  were  admitted  in  our  hospital with  ACS,  without  any  traditional  risk  factors  were  analyzed  for  hsCRP  [highly  sensitive  C  reactive  protein ],  Lp(a)  [Lipoprotein(a)],  Homocysteine  and  uric  acid  level.

Results: 44.29%  of  the  study  population  have  high  values  of  hs-CRP,  more  in  older age  group  but  not  significant (<40 vs >40 yrs) (P=0.79). High  homocysteine  present in 42.86%  of cases,  more  in  older  age ( >40 yrs) (54.55%)  than  <40  years  age  (23.08%) which  is  statistically  significant  (P-0.01).  High  uric  acid  level  found  in  32.86%  of cases  without  any  significant  age  and  sex  difference.  High  Lp(a)  level  is  found  in 41.43%  of  cases  more  among ≥40  years (50%)  than  <40 years (26.92%),  the  difference was  not  found  to  be  statistically  significant. [ Chi-square = 3.587; P=0.058; OR=2.71 95%  CI= 0.95 – 7.7].

Conclusion:  hsCRP  is  most  useful  cost  effective  screening  method  for  ACS  in younger  individual  among  all  other  parameters  in  this  part  of  world .

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