An Unexpected Case of Isolated Left Ventricular Apical Hypoplasia in an Asymptomatic Patient

Rachel Anne Xuereb, Sara Xuereb, Tiziana Felice, Mariosa Xuereb, Alex Borg

Abstract


Isolated left ventricular (LV) apical hypoplasia is a rare type of congenital heart disease. It is often asymptomatic in childhood but may lead to complications later on in life. The proposed mechanism is inadequate LV dilatation during development of the primitive ventricle, resulting in a spherical LV. To our knowledge, we describe for the first time a case of isolated LV apical hypoplasia in an asymptomatic patient, diagnosed on investigation of an abnormal 12-lead resting electrocardiogram (ECG).


Keywords


Isolated left ventricular apical hypoplasia; Cardiac MRI; Congenital; Rare; Asymptomatic

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References


Starmer G, Younge JF, Stewart P. Multimodality imaging of isolated left ventricular apical hypoplasia. Eur Heart J. 2012, 33(5):675. doi: 10.1093/eurheartj/ehr252.

Irving C, Chaudhuri M. Fatal presentation of congenital isolated left ventricular apical hypoplasia. European Journal of Cardio-Thoracic Surgery. 2009, 35(2) p. 368–369. doi:10.1016/j.ejcts.2008.10.039

Fernandez-Valls M, Srichai MB, Stallman AE, White RD. Isolated left ventricular apical hypoplasia: a new congenital anomaly described with cardiac tomography. Heart. 2004, 90(5), p. 552–555. doi: 10.1136/hrt.2003.010637

Patrianakos AP, Protonotaries N, Zacharaki A, Tsatsopoulou A, Parthenakis FI, Vardas PE. Isolated left ventricular apical hypoplasia: a newly recognized unclassified cardiomyopathy. J Am Soc Echocardiogram. 2010, 23(12):1336. doi:10.1016/j.echo.2010.05.014.

Galvao C, Silva P, Magalhaes S, Bettencourt N, Themudo R. Isolated left ventricular apical hypoplasia. Eur Heart J. - Cardiovascular Imaging. 2014, 15(12), p. 1399. doi:10.1093/ehjci/jeu149

Alizadeh SZ, Vojdanparast M, Rezaeian N, Seifi A, Omidvar Tehrani S, Nezafati P. Left ventricular apical hypoplasia: Case report on cardiomyopathy and a history of sudden cardiac death. ARYA Atheroscler. 2016, 12(1), p. 50-4

Orsbonre C, Schmitt M. Isolated left ventricular apical hypoplasia, characterized by cardiac magnetic resonance imaging. Eur Heart J. 2014, 35(46), p. 3303. doi:10.1093/eurheartj/ehu316

Baroni M, Pedrotti P, Nava S, Giannattasio C, Roghi A. Cardiac magnetic resonance imaging of left ventricular apical hypoplasia in two complex congenital clinical syndromes. Circa J. 2014, 78(6), p.1507-9. doi:10.1253/circj.cj-13-1555

Skidan VI, Kuznetsova T, Pavlyukova EN, Nartsissova GP. Isolated left ventricular apical hypoplasia with myocardial non-compaction: a case report. Eur Heart J Case Rep. 2019, 31;4(1):1-6. doi: 10.1093/ehjcr/ytz215

Braga C, Silva P, Magalhaes S, Bettencourt N, Themudo R. Isolated left ventricular apical hypoplasia. Eur Heart J Cardiovasc Imaging. 2014, 15(12), p. 1399. doi:10.1093/ehjci/jeu149

Shewan LG, Coats AJS, Henein MY. Authors’ Responsibilities and Ethical Publishing. International Cardiovascular Forum Journal. 2018,13:3-4. doi:10.17987/icfj.v13i0.525




DOI: https://doi.org/10.17987/icfj.v20i0.675

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