Heart Rate Variability in a Patient with Coronavirus Disease 2019

Reiner Buchhorn, Christoph Baumann, Christian Willaschek

Abstract


This case study investigates the heart rate (HR) and heart rate variability (HRV) in a patient with coronavirus disease 2019 (COVID-19). We report the case of a 58-year old male who contracted COVID-19. During his disease, 24-hour Holter electrocardiography (ECG) was performed continuously. For comparison, his 24-hour Holter ECGs from the previous 10 years were available. In this patient, COVID-19 was associated with a decrease in HR and a paradoxical decline in HRV. An abrupt decline in HRV and a decrease in HR may signal the onset of COVID-19 before common symptoms such as dry cough or fever appear. In addition, HRV and HR measurements may help to evaluate the course of the disease.


Keywords


COVID-19 virus disease; Autonomic nervous system; Electrocardiography; Heart rate

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References


Boyett, M., Wang, Y., & D'Souza, A. (2019). CrossTalk opposing view: Heart rate variability as a measure of cardiac autonomic responsiveness is fundamentally flawed. The Journal of physiology, 597(10), 2599-2601. doi:10.1113/JP277501

Boyett, M. R. (2017). Last Word on Point:Counterpoint. 123(3), 694-694. doi:10.1152/japplphysiol.00542.2017

Gąsior, J. S., Sacha, J., Jeleń, P. J., Zieliński, J., & Przybylski, J. (2016). Heart Rate and Respiratory Rate Influence on Heart Rate Variability Repeatability: Effects of the Correction for the Prevailing Heart Rate. Frontiers in Physiology, 7, 356-356. doi:10.3389/fphys.2016.00356

Monfredi, O., Lyashkov, A. E., Johnsen, A.-B., Inada, S., Schneider, H., Wang, R., . . . Boyett, M. R. (2014). Biophysical characterization of the underappreciated and important relationship between heart rate variability and heart rate. Hypertension, 64(6), 1334-1343. doi:10.1161/HYPERTENSIONAHA.114.03782

Sacha, J. (2013). Why should one normalize heart rate variability with respect to average heart rate. Front Physiol, 4, 306. doi:10.3389/fphys.2013.00306

Sammito, S., & Bockelmann, I. (2016). Reference values for time- and frequency-domain heart rate variability measures. Heart Rhythm, 13(6), 1309-1316. doi:10.1016/j.hrthm.2016.02.006

Shewan LG, C. A., Henein MY. . (2018). Authors’ Responsibilities and Ethical Publishing. . International Cardiovascular Forum Journal; doi: DOI: 10.17987/icfj.v13i0.525

van den Berg, M. E., Rijnbeek, P. R., Niemeijer, M. N., Hofman, A., van Herpen, G., Bots, M. L., . . . Kors, J. A. (2018). Normal Values of Corrected Heart-Rate Variability in 10-Second Electrocardiograms for All Ages. Frontiers in Physiology, 9, 424-424. doi:10.3389/fphys.2018.00424

WHO. (2020). https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---3-march-2020.




DOI: https://doi.org/10.17987/icfj.v20i0.685

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